Pall Corporation

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Gene Therapy 
Technical Paper

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In the news: Abeona Therapeutics scales up production of rAAV using AAV293 suspension cells in the AllegroTM STR bioreactor system.

Just published by Cell and Gene Therapy Insights, "Scalability comparison between 50 and 500 liter stirred tank bioreactor for production of rAAV viral vector" provides new insights to scaling up production of high-titer and high-quality viral vectors at clinical and commercial scales.

This study demonstrates:

  • Control of key process parameters enabled a scalable vector production process between the 50 L and 500 L scale using Allegro STR single-use bioreactors.
  • The Allegro STR single-use bioreactor family provides a scalable solution for gene therapy customers.
  • Pall's Allegro STR bioreactor provides a compact, ergonomic and intuitive turn-key bioreactor design concept to maximize usability and process assurance, while maintaining optimal performance.
Download your paper today and learn how Abeona Therapeutics scaled up production fast!

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