Continuous Chromatography
SCALABILITY FROM PROCESS DEVELOPMENT
TO cGMP MANUFACTURING
LEARN HOW MERCK MADE THE
TRANSITION FROM PROCESS
DEVELOPMENT TO
MANUFACTURING SCALE.
HIGHLIGHTS INCLUDE:
TRANSITION FROM PROCESS
DEVELOPMENT TO
MANUFACTURING SCALE.
HIGHLIGHTS INCLUDE:
- UP TO 80% REDUCTION IN
PROTEIN A VOLUME - THE BATCH PROCESS WAS
CONVERTED TO CONTINUOUS AND
SCALED UP ALL WITHIN 3 WEEKS - PRODUCT QUALITY ATTRIBUTES WERE
SIMILAR THROUGHOUT SCALE-UP
